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   exploring the biological potential of cruciata taurica (pall. ex willd.) ehrend.: evaluating antibacterial, antioxidant, antidiabetic, and cytotoxic properties  
   
نویسنده khalil-moghaddam shiva ,moghimi roya ,efferth thomas ,mousavian sajedeh
منبع trends in phytochemical research - 2024 - دوره : 8 - شماره : 2 - صفحه:131 -140
چکیده    This study focused on the biological properties of cruciata taurica, a plant found in the irano-turanian region, which has not been extensively studied in terms of its phytochemical and biological activities. the methanolic extract of the plant was obtained and its cytotoxic, antibacterial, antidiabetic, and antioxidant properties were investigated. the antibacterial activity of the fractions was evaluated using broth microdilution method, while the antioxidant properties were assessed through the dpph assay and the cytotoxic properties were determined using the rra assay. this study revealed that the residual aqueous fraction exhibited the highest extraction yield and the most potent antioxidant activity. the etoac fraction showed strong antibacterial activity against certain bacteria, while the n-hexane fraction exhibited greater antidiabetic effects. additionally, the etoac fraction was found to be the most cytotoxic. overall, the study suggested that c. taurica has potential therapeutic applications due to its various biological properties.
کلیدواژه bioactivity ,cancer ,cruciata taurica (pall. ex willd.) ehrend. ,cytotoxic ,ethnopharmacology ,multidrug resistance ,plant extract
آدرس islamic azad university, yadegar-e-imam khomeini (rah) shahre rey branch, department of biology, iran, university of mazandaran, faculty of chemistry, department of organic chemistry, iran, johannes gutenberg university mainz, institute of pharmaceutical and biomedical sciences, department of pharmaceutical biology, germany, islamic azad university, tehran science and research branch, departmant of biology, iran
پست الکترونیکی mousavian124215@yahoo.com
 
     
   
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