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biological activities of protocorms and stems extracts of dendrobium transparens
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نویسنده
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joshi pusp raj ,thapa bir bahadur ,chand krishna ,maharjan lasta ,paudel mukti ram ,pant basant ,pant bijaya
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منبع
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trends in phytochemical research - 2024 - دوره : 8 - شماره : 2 - صفحه:122 -130
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چکیده
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This study assessed the phenolic and flavonoid contents, and antioxidant, antibacterial, as well as cytotoxic properties of the protocorm extract of dendrobium transparens and compared it to its wild equivalents. methanol was used to extract compounds from the stems (dtse) and protocorms (dtpe). dtse contained 61.889 mg qe and 82.00 mg gae per gram of quercetin and gallic acid, respectively. at a concentration of 191.23 μg/ml, dtse exhibited a 50% dpph radical scavenging efficiency. compared to the 3t3 cell line (2108.87 μg/ml), the dtpe's cytotoxic ability against the hela (229.30 μg/ml) and u251 (213.90 μg/ml) cell lines was found to be significantly stronger. however, the u251 cell line was strongly cytotoxic to dtse (75.84 μg/ml). at a dose of 2000 mg/kg, neither dtse nor dtpe caused any discernible harm in mice. they could inhibit the growth of acinetobacter baumannii, escherichia coli, klebsiella pneumoniae, pseudomonas aeruginosa, and staphylococcus aureus. based upon the experimental results, the wild stems and protocorms were found to be alternatives suitable for creating pharmacologically bioactive substances.
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کلیدواژه
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antibacterial activity ,antioxidant activity ,dendrobium transparens ,mtt ,protocorms ,total flavonoid content (tfc) ,total phenolic content (tpc)
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آدرس
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tribhuvan university, central department of botany, nepal, tribhuvan university, central department of botany, nepal, annapurna research center, nepal, annapurna research center, nepal, tribhuvan university, central department of botany, nepal, annapurna research center, nepal. annapurna neurological institute & allied sciences, nepal, tribhuvan university, central department of botany, nepal
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پست الکترونیکی
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bijaya.pant@cdb.tu.edu.np
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Authors
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