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chemical composition and cytotoxicity of the essential oil of tanacetum abrotanifolium (l.) druce (asteraceae) from iran
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نویسنده
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sonboli ali ,ghilichpour sepideh ,farhadpour mohsen ,arman mitra
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منبع
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trends in phytochemical research - 2022 - دوره : 6 - شماره : 3 - صفحه:242 -247
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چکیده
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Chemical composition of the essential oil obtained from aerial parts of tanacetum abrotanifolium (l.) druce (asteraceae) was investigated. plant sample was collected at full flowering stage from west azerbaijan province of iran. the hydrodistilled essential oil was analyzed by gc-fid and gc-ms. the major compounds were found to be (e)-sesquilavandulol (26.6%), camphor (16.2%) and 1,8-cineole (12.9%). cytotoxicity activity of the oil was evaluated against four cancer cell lines, of which ic50 values estimated to be 312, 312, 625 and 1250 μg oil/ml for the monkey kidney vero, human breast adenocarcinoma (mcf7), choriocarcinoma (jet 3) and human colon adenocarcinoma (sw480) cell lines, respectively.
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کلیدواژه
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aerial parts ,asteraceae ,cytotoxicity activity ,essential oil ,gc-ms analysis ,tanacetum abrotanifolium
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آدرس
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shahid beheshti university, medicinal plants and drugs research institute, department of biology, iran, islamic azad university, pharmaceutical sciences branch, iran, national institute of genetic engineering and biotechnology (nigeb), department of plant bioproducts, iran, payame noor university, department of biology, iran
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Authors
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