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chemical composition of leplaea mayombensis (pellegrin) staner
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نویسنده
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djeukeu charlie kenmoe ,maza hermine laure djomkam ,kenmogne ariane kouam ,sewald norbert ,wansi jean duplex ,vardamides juliette catherine
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منبع
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trends in phytochemical research - 2021 - دوره : 5 - شماره : 2 - صفحه:105 -109
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چکیده
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One new coumarinolignan, cleomiscosin f (1) along with ten known compounds namely 3,4-secotirucalla-4(28),7,24-trien-21-hydroxy-21,23-epoxy-3-oic acid (2), 3,4-secotirucalla-4(28),7,24-trien-3,21-dioic acid (3), ceramid a (4), ceramid b (5), mayombensin (6), aridanin (7), stigmasterol and β-sitosterol and their glucosides were isolated from the seeds and roots of leplaea mayombensis (meliaceae). the structures of the compounds were elucidated based on the interpretation of their spectroscopic data. some of the isolated compounds (3, 4 and 5) were tested in vitro against bacteria strains escherichia coli, bacillus subtilis, pseudomonas agarici, and micrococcus luteus. compound 3 displayed good activity against bacillus subtilis, micrococcus luteus, and pseudomonas agarici with mic values of 1.7, 2.3 and 9.8 μm, respectively; while compound 4 showed significant activity against micrococcus luteus with mic value of 11.9 μm.
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کلیدواژه
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antibacterial activity ,coumarinolignan ,leplaea mayombensis ,minimum inhibitory concentration
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آدرس
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university of douala, faculty of science, department of chemistry, cameroon, university of douala, faculty of science, department of chemistry, cameroon, bielefeld university, department of chemistry, germany, bielefeld university, department of chemistry, germany, university of douala, faculty of science, department of chemistry, cameroon, university of douala, faculty of science, department of chemistry, cameroon
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پست الکترونیکی
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jucathmas@yahoo.fr
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Authors
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