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a new phenylpropanoid glucoside from psorospermum tenuifolium kotschy (hypericaceae)
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نویسنده
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happi gervais mouthé ,mbobda alexis sylvain w. ,frese marcel ,kouam simeon fogue ,tchouankeu jean claude ,lenta bruno ndjakou ,sewald norbert
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منبع
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trends in phytochemical research - 2021 - دوره : 5 - شماره : 1 - صفحه:31 -36
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چکیده
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A new phenylpropanoid glycoside, namely psorospermoside (1) was obtained from the psorospermum tenuifolium bark extract together with eleven known compounds. their structures were elucidated using spectroscopic and spectrometric methods including 1d, 2d-nmr and esi-ms, as well as by comparison of their data with those reported in the literature. all the isolated compounds were assessed for their cytotoxicity effect on the human cervix carcinoma cell line kb3-1. emodin (2) and its congener 2-geranylemodin (3) displayed significant cytotoxicity with ic50 values of 11.4 μm and 19 μm, respectively. furthermore, the chemophenetic significance of the isolated compounds was also discussed.
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کلیدواژه
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psorospermum tenuifolium ,phenylpropanoid glucoside ,psorospermoside ,emodin ,2-geranylemodin ,cytotoxicity
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آدرس
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university of bamenda, higher teacher training college, department of chemistry, cameroon. bielefeld university, faculty of chemistry, germany, university of yaounde i, higher teacher training college, department of chemistry, cameroon, bielefeld university, faculty of chemistry, germany, university of yaounde i, higher teacher training college, department of chemistry, cameroon, university of yaounde i, faculty of sciences, department of organic chemistry, cameroon, university of yaounde i, higher teacher training college, department of chemistry, cameroon, bielefeld university, faculty of chemistry, germany
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پست الکترونیکی
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norbertsewald@uni-bielefeld.de
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Authors
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