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chemical constituents from the leaves and liana of salacia nitida (benth.) n.e.br. (celastraceae) and their antimicrobial activities
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نویسنده
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mba’ning brice m. ,ateba joël e. t. ,awantu angelbert f. ,amaral luciana s. ,happi gervais m. ,neumann beate ,stammler georg ,lenta bruno ,ngouela silvère a. ,malavazi iran ,tsamo etienne ,sewald norbert ,rodrigues-filho edson
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منبع
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trends in phytochemical research - 2019 - دوره : 3 - شماره : 2 - صفحه:83 -90
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چکیده
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One 4′-hydroxy-2,4,6-trimethoxybenzophenone (1) was isolated from the liana and leaves of salacia nitida (benth.) n.e.br., together with n-hexacosane (2), 29-hydroxyfriedelane (3), 3β-friedelinol (4), n-hexacosan-1-ol (5), n-octacosan-1-ol (6), mangiferin (7), β-sitosterol- 3-o-β-d-glucopyranoside (8), friedelin (9), 30-hydroxyfriedelin (10), salaspermic acid (11), 22β-epi-maytenfolic acid (12), orthosphenic acid (13), maltose (14), d-mannitol (15), cangoronine (16), 7-hydroxyfriedelane-1,3-dione (17), tingenone (18), pristimerin (19), α-amyrin acetate (20), β-sitosterol (21), stigmasterol (22), 21-hydroxyfriedelan-3- one (23), abruslactone a (24) and 2α-hydroxypopulnonic acid (25). the structures of the isolated compounds were established by means of spectroscopic analysis. in addition, the structure of (1) was confirmed by its x-ray diffraction. compounds (1), (7), (10)- (11), (13), (16)-(19) and (25) were evaluated for their antimicrobial activities. compound (18) showed a significant activity against staphylococcus aureus (mic=23.8 μm), while compounds (11) and (19) exhibited moderate inhibiting effect against staphylococcus aureus (mic=53.8 μm) and candida glabrata (mic=105.9 μm), respectively.
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کلیدواژه
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salacia nitida (benth.) n.e.br ,leaves and liana ,benzophenone ,nmr spectroscopy ,x-ray diffraction ,antimicrobial activity
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آدرس
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university of yaoundé 1, faculty of science, department of organic chemistry, cameroon, university of yaoundé 1, faculty of science, department of organic chemistry, cameroon, university of bamenda, faculty of science, department of chemistry, cameroon, universidade federal de são carlos, departamento de química, brazil, university of yaoundé 1, higher teacher training college, department of chemistry, cameroon, bielefeld university, faculty of chemistry, department of chemistry, germany, bielefeld university, faculty of chemistry, department of chemistry, germany, university of yaoundé 1, higher teacher training college, department of chemistry, cameroon, university of yaoundé 1, faculty of science, department of organic chemistry, cameroon, universidade federal de são carlos, departamento de genética e evolução, brazil, university of yaoundé 1, faculty of science, department of organic chemistry, cameroon, bielefeld university, department of chemistry, organic and bioorganic chemistry, germany, universidade federal de são carlos, departamento de química, brazil
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پست الکترونیکی
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edinho@pq.cnpq.br
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Authors
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