Evaluation of Compressive Mechanical Properties of the Radial Bone Defect Treated with Selected Bone Graft Substitute Materials in Rabbit

objective- to determine the effect of selected bone graft on the compression properties of radialbone in rabbit.design- experimental in vivo study.animals- a total of 45 adult male new zealand white rabbits.procedures- the rabbits were anesthetized and a one-cm-full thickness piece of radial bone wasremoved using oscillating saw in the all rabbit. the rabbits were divided into 5 groups on thebasis of the material used to fill the bone defect: group 1: the paste of bone cement calciumphosphate; group ii: the paste of calcium phosphate mixture with type i collagen; group iii:tricalcium phosphate mixed with hydroxyapatite (tcp & hp) with 5% porosity; group iv: thesame scaffold as group iii with 10% porosity; and group v: the same scaffold as group iii andiv with 20% porosity, with 9 rabbits in each group. subsequently subdivided into 3 subgroupsof 3 rabbits each.results- there was a significant increase in compression properties of radial bone in the group iiand v in 2nd and 3rd months as compared with groups i, iii and iv. the mean endurable crackstrengthin group ii and v were slightly higher than that of normal radius (p<0.05).conclusion and clinical relevance- application of calcium phosphate paste with type icollagen and scaffold of tricalcium phosphate with hydroxyapatite having 20% porosityindicated to have positive effect in integral formation of qualitative callus at the site of fractureand early re-organization of callus to regain mechanical strength too.