Comparison of Lidocaine, Xylazine, and A Combination of Lidocaine and Xylazine For Caudal Epidural Analgesia in Dromedary Camels

Objective- this study was performed to investigate the analgesic effects of lidocaine, xylazine and lidocaine/xylazine combination in epidural anesthesia in dromedary camels. design- experimental study animals- fifteen healthy immature dromedary camels methods- the camels were randomly designed in 3 equal groups. in group l: lidocaine 2% (0.22 mg/kg), in group x: xylazine 2% (0.17 mg/kg), and in group lx: a combination of lidocaine 2% (0.22 mg/kg) and xylazine 2% (0.17 mg/kg) were injected into the first intercoccygeal epidural space. analgesia, sedation, ataxia, and effect on cardiopulmonary, rectal temperature were recorded at different intervals before (baseline) and after the drug administration. results- epidural lidocaine, xylazine and their combination produced analgesia in the tail, anus and perineum. onset time of perineal analgesia in groups l and lx was significantly shorter than group x. duration of complete perineal analgesia in group x and lx was significantly longer than group l. mild to moderate sedation was observed in groups x and lx, whilst the camels in group l were alert and nervous during the study. ataxia was observed in all test subjects and was more severe in group l and lx. significant depression in heart rate, respiratory rate, and rectal temperature values were observed in groups x and lx in some measurement points of the study. conclusion and clinical relevance- according to the results of present study, it could be concluded that a combination of lidocaine and xylazine administered epidurally to dromedaries produces an effective, safe, with more rapid onset of longer perineal analgesia, when compared with either agent alone.