comparative evaluation of standing and lateral recumbency restraint positions for rumenotomy based on transforming growth factor-β responses in kano-brown goats

Objective- comparative evaluation of standing and lateral recumbent restraint positions for rumenotomy based on transforming growth factor-β (tgf-β) concentrations of kano-brown goats (kbgs). design- experimental study animals- twenty-four kbgs eighteen kbgs of both sexes diagnosed of rumen foreign body impaction (rfbi), were allocated to groups a, b and d. six other kbgs free of rfbi were assigned to group c as control. procedures- groups a and b were restrained in lateral recumbency while group d in a fabricated mobile small ruminant surgical chute (msrsc). serum samples stored at -20 ℃ until elisa, were obtained pre-rumenotomy (pre) and post-rumenotomy, at 0, 5, 24, 48 and 72 hours, and subsequently at weeks 1, 2, and 3. group c had no surgery while a, b and d had rumen skin clamp fixation, stay suture rumenotomy and mobile small ruminant surgical chute rumenotomy, respectively. results- the post-rumenotomy mean concentrations of tgf-β for groups a, b and d at 0 hour (81.97 ± 24.12, 71.26 ± 10.28 and 58.51 ± 6.44 ng/l, respectively) were higher than the mean pre-rumenotomy values (38.34 ± 3.66, 41.31 ± 4.90 and 44.91 ±4.10 ng/l, respectively) but were not significantly different (p > 0.05). as the mean tgf-β concentration in the males of the different experimental groups did not differ significantly (p > 0.05), the females of group b had significantly higher (p < 0.05) mean concentrations than those of group d and c females at 48 hours post-rumenotomy. conclusions and clinical relevance- lateral recumbency restraint position rumenotomy was associated with more severe post-surgical stress than standing restraint based on role switching of tgf-β in this study. this suggests comparative advantage of standing recumbency restraint rumenotomy over the conventional lateral recumbency restraints position in goats.