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   Comparison of Lidocaine-Distilled Water and Lidocaine-Mgso4 Mixture in Epidural Anesthesia of Dog  
   
نویسنده Dehghani Saifollah ,Bigham Sadegh Amin
منبع Iranian Journal Of Veterinary Surgery - 2007 - دوره : 2 - شماره : 3 - صفحه:59 -65
چکیده    Objective- to compare the lidocaine-mgso4 combination with lidocaine-distilled water inthe epidural of indigenous awake dogs.design- prospective experimental study.animals- five young (12±2 months) female indigenous dogs weighting (10.74 ± 0.44 kg).procedures- epidural anesthesia was produced in all dogs with 2% lidocaine (1ml/4.5 kgbody weight) with 1 ml distilled water and two weeks later repeated by lidocaine (1ml/4.5kg) with 1 ml of 10% mgso4. time to recumbency, onset time, duration of analgesia andcranial spread of analgesia and standing time were recorded. heart rate, respiratory rateand body temperature were recorded at 0 minute prior to epidural administration of eachtreatment as a base line values and at 5, 10, 15, 30, 60 and 75 minutes afterwards. statisticalanalysis included paired student t-test and anova (spss, soft ware of windows). p<0.05was considered as significant level.results- significant difference (p<0.05) was noted for onset of analgesia betweenlidocaine-distilled water (2.04 ± 0.14 min) and lidocaine-mgso4 (4.70 ± 0.20 min).lidocaine-mgso4 produced analgesia of significantly longer duration (185 ± 5.13 min)than that of lidocaine - distilled water (49 ± 4.5 min). lidocaine-distilled water producedrecumbency at 1.48 ± 0.106 min after epidural administration but lidocaine-mgso4 didnot produce any recumbency throughout the study. time to standing after epidural injectionof lidocaine-distilled water was 49.8 ± 1.56 min.conclusion and clinical relevance the combination of lidocaine-mgso4 producedanalgesia longer than lidocaine-distilled water. long lasting obstetrical and surgicalprocedures could commence relatively soon after epidural injection of lidocaine-mgso4and could be completed without re-administration of anesthetic agent.
کلیدواژه Mgso4 ,Lidocaine ,Canine ,Epidural Anesthesia.
آدرس Shiraz University, Faculty Of Veterinary Medicine, Department Of Clinical Sciences, ایران, Shahrekord University, Faculty Of Veterinary Medicine, Department Of Clinical Sciences, ایران
پست الکترونیکی sdehghan04@yahoo.com
 
 

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