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   Caudal Extradural Analgesia With Lidocaine, Xylazine, and A Combination of Lidocaine and Xylazine in the Iranian River Buffalo (Bubalus Bubalis)  
   
نویسنده Saifzadeh Siamak ,Pourjafar Mehrdad ,Dalir Naghadeh Bahram
منبع Iranian Journal Of Veterinary Surgery - 2007 - دوره : 2 - شماره : 3 - صفحه:7 -13
چکیده    To compare the time of onset, duration of action and the extent of analgesiaproduced by a lidocaine/xylazine combination with that produced by lidocaine and xylazinealone after injection into the caudal extradural space of the iranian river buffalo.design- observer-blind prospective descriptive trial, latin square design.animals- eleven adult (aged over 2 years) female non-gravid healthy iranian riverbuffaloes (bubalus bubalis), weighing from 450 to 650 kg.procedure- caudal extradural analgesia was achieved in buffaloes on 3 occasions at 14-dayintervals by injection of 2% lidocaine (l; 0.22 mg kg-1), 2% xylazine (x; 0.05 mg kg-1), anda combination of 2% lidocaine(0.22 mg kg-1) / 2% xylazine (lx; 0.05 mg kg-1) in a latinsquare design. analgesia was determined by the lack of response to pin-prick andhaemostat pressure in the skin of the caudal areas.results- onset of analgesia for x was significantly longer (5.5 ± 0.7 minutes) than that forl or lx. duration of analgesia was significantly longer for lx (172.3 ± 17.7 minutes) thanfor either drug used alone (lidocaine, 79.5 ± 5.7 minutes; xylazine, 136.4±11.4 minutes). inx and lx groups, the level of analgesia ascended to thoracic segments; however, inlidocaine-treated buffaloes thighs, flank, and udders remained sensitive. in all buffaloes,xylazine, administered either alone or with lidocaine, induced mild to moderate ataxia.conclusions – the lx combination provided a more rapid onset, a longer duration ofanalgesia, and a more cranial spread of analgesic effect compared with either drug alone.clinical relevance: the lx combination may offer a fast and long lastinganesthesia/analgesia to perform obstetrical and surgical procedures without the need for reinjection.
کلیدواژه Lidocaine ,Xylazine ,Caudal Extradural Analgesia ,Buffalo ,Bubalus Bubalis
آدرس Urmia University, Faculty Of Veterinary Medicine, Department Of Clinical Sciences, ایران, Shahrekord University, Faculty Of Veterinary Medicine, Department Of Clinical Sciences, ایران, Urmia University, Faculty Of Veterinary Medicine, Department Of Clinical Sciences, ایران
پست الکترونیکی s.saifzadeh@mail.urmia.ac.ir
 
 

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