Xylazine-Lidocain Combination for Retrobulbar Block in Goats

Objective- this study was performed to investigate the analgesic effects of lidocaine,xylazine and lidocaine/xylazine combination in eye regional anesthesia.design- experimental study.animals- twenty adult goats were randomly designed in 4 groups.procedures- in group l: 10 ml mixture of lidocaine 2% (5 mg/kg bw) and normal saline, ingroup lx: 10 ml mixture of lidocaine 2% (5 mg/kg bw), xylazine 2% (0.05 mg/kg bw) andnormal saline, in group x: 10 ml mixture of xylazine 2% (0.05 mg/kg bw) and normal salineand in group c: 10 ml of normal saline were injected into the retrobulbar space of left eyesvia four point method. onset and duration of eyelids analgesia and glob analgesia/akinesiawere compared between the groups.the images were studied serially and compared anatomically with two dissected head andintact goat skulls.results- the results of this study demonstrated that eye regional anesthesia have not beenobserved in group c. in group x, sedative effect of xylazine without complete loss of eyelidsand glob anaesthesia was observed. there was no significant difference in onset of eyelidsand glob anaesthesia between groups l and lx (p>0.05). duration of eye regional anesthesiain group lx was significantly more than group l (p<0.05). the animals in groups x and lxwere sedated during the study but in group l the animals were alert and nervous.conclusion and clinical relevance- according to results of present study, addition ofxylazine to lidocaine for retrobulbar block causes a sedative effect and increased duration ofeye regional anesthesia.