Synthesis and Characterization With Antimicrobial Studies of Mixed Curcumin Schiff Base –L-Dopa With Divalent Cations Complexes

In the present article, mixed ligand metal (ii) complexes have been synthesized with schiff base (1e, 5z, 6e)-1,7 bis (4-hydroxy-3-methoxyphenyl)-5-(3-hydroxyphenyl) imino) hepta-1,6-dien-3-one derived from curcumin and 3-aminophenol as primary ligand and l-dopa as a secondary ligand. the schiff base act as bidentate and arrange to the metals through the azomethine (c=n) nitrogen and (c=o) oxygen atom. the mode of bonding of the schiff base has been affirmed on the infrared by the uv-visible, 1h, and 13c nmr spectroscopic techniques. the magnetic susceptibility and the uv-vis data of the complexes propose octahedral geometry around the central metal ion. the information appears that the complexes have the structure of [l-m-(l-dopa)] system, where m=mn(ii), ni(ii), cu(ii), zn(ii) and cd(ii). the low conductance of all complexes supports the non-electrolytic nature of the complexes. the biological activity of the complexes was screened against bacteria, (klebsiella and p. staphylococuse and gives a good results anti-fungus c. albicans). all complexes possess the biological activity which has the same activities, and good antimicrobial activity that displays higher activities against fungus compared with bacteria.