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Synthesis, Characterization and Study Biological Activity of Some 1,2,4-Triazin Heterocyclic Derivatives
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نویسنده
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Ahmed Safaa Thamer ,Rasool Shireen R.
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منبع
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Journal Of Medicinal And Chemical Sciences - 2023 - دوره : 6 - شماره : 7 - صفحه:1537 -1547
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چکیده
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A series of some new heterocyclic compounds containing triazin derivatives have been synthesized in many steps sequence. triazine derivatives were prepared through reacting benzil with semicarbazide or thiosemicarbazide to form 5,6-diphenyl-1,2,4-triazin-2(3h)one,5,6-diphenyl-1,2,4-triazine-2(3h)thione, respectively. a hydroxymethylation reaction has been made to the amide group. the hydroxyl group was replaced by azide group. a different substituted triazine rings have been formed using different reagents. the structures of the newly prepared derivatives were identified through more than one technique like (ft-ir, 1h-nmr, and 13c-nmr) for all derivatives.
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کلیدواژه
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Heterocyclic Compounds ,Benzyl ,Triazine Derivatives ,Quinazoline ,Triazole ,Tetrazole ,Amidazoldine
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آدرس
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University Of Babylon, College Of Science, Department Of Chemistry, Iraq, University Of Babylon, College Of Science, Department Of Chemistry, Iraq
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پست الکترونیکی
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sci.shireen.ridha@uobabylon.edu.iq
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Authors
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