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synthesis, examination of various seven rings, and effects on corrosion and fungus
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نویسنده
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jarallah aziz latif ,kareem aseel fadhil
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منبع
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journal of medicinal and chemical sciences - 2023 - دوره : 6 - شماره : 3 - صفحه:532 -539
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چکیده
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The majority of benzodiazepines is administered orally and has various beneficial effects, including psychotropic, anxiolytic, hypnotic, sedative, muscle relaxing, anticonvulsant, and amnesic ones. these include benefits for alcohol dependence, epileptic seizures, irritable disorders, scare, and insomnia. the goal of this study was to create bicycles from benzodiazepines through cyclization steps. all generated compounds were examined by using several analytical techniques, including: ft-ir, 1h-nmr, mass spectroscopy analysis, and other chemical characterization, with formatted compounds being assessed as antifungals and inhibitors. these compounds were utilized to explain biological activity against aspergilla's and candida albicans at various concentrations (5, 10, 15, and 20 mg/ml-1). the findings demonstrated that all compounds were active against all varieties of fungi and that oxazepine, diazepine bicycles, and heteroatoms in the structure inhibited the corrosion of mild steel in 0.5m hcl.
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کلیدواژه
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cycloaddition reaction ,oxazepine ,diazepine ,corrosion ,schiff bases ,antifungal activity
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آدرس
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al-esraa university college, department of medical labs. techniques, iraq, university of babylon, college of pharmacy, iraq
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پست الکترونیکی
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aseelpharmacy77@gmail.com
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Authors
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