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evaluation of rats’ biochemical markers in artemisia annua linn. extract after lead toxicity
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نویسنده
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al-musawi adil turki ,mohammed sudad jasim ,abdul-razzaq aliaa saadoon
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منبع
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journal of medicinal and chemical sciences - 2022 - دوره : 5 - شماره : 7 (Special - صفحه:1247 -1252
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چکیده
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This research aimed to evaluate the impact of artemisia annua l. (a. annua l.) on liver and kidney functions following lead-induced injury that was extracted from the plant by using ethanol. forty male rats were divided into 4 classes (ten rats per group), g1 called negative regulation, g2 administered 15 mg/kg of lead acetate per day for 15 days orally, g3 administered a. annua l. extract at 100 mg/ml ip for 2 weeks, and g4 administered 15 mg/kg of lead acetate per day for 15 days, and then handled a. annua l. at (100 mg/kg b.wt) for two weeks. as a result of the procedure, blood samples were aspirated for serum isolation, the serum was used to estimate alanine aminotransferase (alt), aspartate aminotransferase (ast), creatinine, and urea. the present findings showed a significant (p≤0.05) increase in levels of ast and alt in g2 compared with g1 and g3 which showed normal values, while g4 showed a significant decrease in alt and ast levels as compared with g1 and g3, whereas g4 displayed a significant (p≤0.05) reduction popular levels of urea, creatinine g 2 related to g1 and g3 which revealed normal values.
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کلیدواژه
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a. annua l.extracted ,rats ,lead toxicity ,biochemical markers
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آدرس
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university of baghdad, market research and consumer protection centre, iraq, university of baghdad, market research and consumer protection centre, iraq, university of baghdad, market research and consumer protection centre, iran
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پست الکترونیکی
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alia.sadon@yahoo.com
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Authors
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