A Journey Towards Fecl3 Catalysed Synthesis of Multisubstituted Pyrrole

An efficient procedure was developed for the synthesis of different derivatives of 3,4- disubstituted pyrrole using tosmic with ethyl cinnamate in dmf and lithium hydroxide monohydrate as a base. moreover, trisubstituted pyrrole was synthesized using nitrostyrene, ethyl-propiolate and benzylamine in toluene as a reaction medium. this reaction was catalysed by fecl3. this strategy was further modified to synthesized tetra and penta substituted pyrrole using ethanol as a reaction medium keeping other conditions intact. this method is very economical and successfully utilized for the synthesis of its derivatives with moderate to good yields.