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efficient protocol for the production of pyrimido[4,5-b] quinolines using an organic-inorganic hybrid catalyst
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نویسنده
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dianat manije ,zare abdolkarim ,hosainpour monavvar
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منبع
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asian journal of nanoscience and materials - 2021 - دوره : 4 - شماره : 4 - صفحه:282 -289
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چکیده
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In this work, an efficient protocol for the synthesis of pyrimido[4,5-b]quinolines was reported. the one-pot multi-component reaction of arylaldehydes, barbituric acid (or 2-thiobarbituric acid) and anilines in the presence of an organic-inorganic hybrid material namely tetramethyl-n-(silica-n-propyl)-n′-sulfonic acid-ethylenediaminium chloride/mesylate ([tssecm]) afforded the mentioned compounds. this protocol has several advantages including, high yields (86-95%), relatively short reaction times (110-120 min), recyclability of the catalyst and easy purification of the products without column chromatography.
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کلیدواژه
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pyrimido[4 ,5-b]quinoline; organic-inorganic hybrid catalyst n ,n′ ,n′-tetramethyl-n-(silica-n-propyl)-n′-sulfonic acid-ethylenediaminium chloride/mesylate ([tssecm]) multi-component reaction
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آدرس
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payame noor university, department of chemistry, iran, payame noor university, department of chemistry, iran, payame noor university, department of chemistry, iran
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پست الکترونیکی
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nooraniii@yahoo.com
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Authors
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