embedded ag nps in cysteine-poly (acrylic acid) hydrogel with antibacterial activity

In this research, ag nps were loaded on cysteine modified poly(acrylic acid) (paa) hydrogel. obtainedcysteine-hydrogel (chydrogel) having different functional groups could stabilize ag nps better than un-modified hydrogel due to the presence of disulfid bondings. first, obtained paa hydrogel from radical polymerization was conjugated with cysteine-hydrochloride (cys) through amidation reaction and then was used as a substrate and stabilization reagent for ag ions. ag ions were reduced on chydrogel in the presence ofnabh4 as reducing reagent. the resultant nanocomposite was well characterized by using uv–vis, ft-ir, xrd and sem techniques. furthermore, the resultant ag nps on the surface of chydrogel showedhigh antibacterial behavior against gram-negative e. coliand gram-positives. aureusdue to the high reaction of thiol-functions with the outer cell surface