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   synthesis and bioactivity assessment of therapeutic deep eutectic solvents for potential pharmaceutical applications  
   
نویسنده mohammed taghreed hassanin ibrahim ,el enshasy hesham ali ,abidin mohamad zainal ,tan li ting ,sukmawati dalia ,jafari mohammad alim
منبع advanced journal of chemistry-section a - 2025 - دوره : 8 - شماره : 12 - صفحه:1978 -1994
چکیده    The increasing need for environmentally friendly solvents in the pharmaceutical field highlights the significance of developing novel strategies to address various obstacles. the primary focus of this review is on the advancement of novel active pharmaceutical ingredient (api) based des called therapeutic deep eutectic solvents (thedess), with a comprehensive investigation into their different physicochemical characteristics such as thermal stability, viscosity, and surface tension. furthermore, an in-depth analysis was conducted to assess the multifunctional capabilities of the prepared thedes, specifically in terms of their antioxidant and antimicrobial properties. the outcomes of this study significantly contribute to the knowledge advancement regarding thedess, shedding light on their potential to address sustainability challenges in the pharmaceutical industry. moreover, the study results highlight the encouraging possibilities offered by thedess in drug delivery systems and therapeutic treatments, suggesting a prospective shift in pharmaceutical approaches towards more sustainable and effective resolutions.
کلیدواژه therapeutic deep eutectic solvents ,active pharmaceutical ingredient ,des ,synthesis ,pharmaceutical approaches
آدرس universiti teknologi malaysia (utm), faculty of science, demaprtment of chemistry, malaysia, universiti teknologi malaysia (utm), innovation centre in agritechnology for advanced bioprocessing (ica), faculty of chemical and energy engineering, malaysia. city of scientific research and technology applications (srta), malaysia, universiti teknologi malaysia (utm), faculty of science, demaprtment of chemistry, malaysia, sateera sdn. bhd., malaysia, universitas negeri jakarta (unj), faculty of mathematics and natural sciences, biology department, indonesia, monash university, school of chemistry, faculty of science, australia
پست الکترونیکی mohammad.jafari@monsh.edu
 
     
   
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