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Antibacterial Activity of Bis(Indolyl) Methane Derivatives Against Staphylococcus Aureus
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نویسنده
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Bahe Anil Kumar ,Das Ratnesh ,Naikoo Gowhar Ahmad ,Kosti Pankaj ,Kashaw Sushil
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منبع
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Advanced Journal Of Chemistry-Section A - 2020 - دوره : 3 - شماره : 6 - صفحه:722 -729
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چکیده
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In the present study, we successfully synthesized a series of indoles with a variety of aromatic aldehydes via one-pot route. the excellent results of the bis(indoly) methane (bim) derivatives was obtained at the presence of 5.0 mol% p-toluene sulfonic acid in acetonitrile at room temperature using conventional process. all the as-synthesized compounds were bioactive. the synthesized bim derivatives were evaluated for the antibacterial activity (in vitro) against the staphylococcus aureus, and the results were compared with the standard kanamycin. the results confirmed that, majority of the as-synthesized compounds revealed splendid antibacterial activity.
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کلیدواژه
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Antibacterial Activity ,Bis(Indolyl) Methane Derivatives ,Catalyst ,Kanamycin ,Staphylococcus Aureus (Mtcc1144)
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آدرس
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Dr. Harisingh Gour Central University, Heterocyclic Synthesis And Electro Analytical Laboratory, Department Of Chemistry, India, Dr. Harisingh Gour Central University, Heterocyclic Synthesis And Electro Analytical Laboratory, Department Of Chemistry, India, Dhofar University, College Of Arts And Applied Sciences, Department Of Mathematics And Sciences, Oman, Dr. Harisingh Gour Central University, Heterocyclic Synthesis And Electro Analytical Laboratory, Department Of Chemistry, India, Dr. Hari Singh Gour University, Department Of Pharmaceutical Science, India
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پست الکترونیکی
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sushilkashw@gmail.com
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Authors
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