Correlation between Inflammatory and Hematologic Biomarkers and Cardiovascular Outcomes Among CCU and Post-CCU PatientsDiagnosed with Acute Coronary Syndrome: A Retrospective Study

Background: deaths associated with the acute coronary syndrome (acs) remain high among cardiac/coronary care unit (ccu) and post-ccu patients. recently, researchers have looked for inexpensive and reliable prognostic indicators as alternatives to the expensive pro- brain natriuretic peptide (probnp) in acs patients to predict adverse outcomes. methods: we retrieved the complete blood count (cbc) records of acs patients and calculated values for plateletcrit (pct), mean platelet volume (mpv), and neutrophil-to-lymphocyte ratio (nlr). we also recorded acs diagnostic methods, duration of hospital stays (ccu and post-ccu), and therapeutic modalities. we considered outcomes such as death, positive or negative troponin, st-elevation, ejection fraction <45, and history of arrhythmia. results: the multivariate model using forward stepwise logistic regression showed that the history of arrhythmia (or=124.052, p= 0.001), positive troponin (or=47.545, p=0.002), hospitalization period (or=2.376, p=0.001), c-reactive protein (crp) (or=1.359, p=0.001), and pct (or=2.018, p=0.001) are independent predictors of mortality. conclusion: crp and pct are considered independent predictors of mortality among ccu and post-ccu patients diagnosed with acs. however, the prognostic significance of nlr and mpv needs to be confirmed by further investigations.