Is Mean Platelet Volume a Useful Predictor of Hospital Mortality in Covid-19 Patients?

Background: elevated mean platelet volume (mpv) can indicate the activation of platelets and the coagulation cascade, which has been suggested as a predictor of mortality in some diseases. the aim of this study was to investigate the role of mpv in predicting hospital mortality in patients with covid-19. methods: this was a cross-sectional single-center retrospective study. the data of all patients with a pcr-confirmed diagnosis of covid-19 hospitalized within a 3-month period were analyzed. the patients’ files were reviewed, and the data were recorded into a checklist, including demographic characteristics, underlying diseases, and laboratory test results. hospital mortality was designated as the main outcome of the study. results: a total of 201 covid-19 patients, confirmed by pcr, were included in this study. in-hospital mortality was observed in 28 patients (13.9%). the results of univariate regression analysis revealed that the triage level, history of chronic pulmonary disease, age, oxygen saturation, lymphocyte count, bun, cr, and crp were significantly related to in-hospital mortality. however, mpv showed no significant relationship with in-hospital mortality. conclusion: low triage level, advanced age and hypoxia predicted a higher risk of in-hospital mortality in covid-19 patients. the role of mpv as a predictor of patient outcome in covid-19 remains inconclusive, necessitating further studies with larger sample sizes.