Relationship Between Cardiac and Liver Markers with In-hospital Mortality in COVID-19 Patients

Background: covid-19 caused by the severe acute respiratory syndrome coronavirus 2 (sars-cov-2) infections has turn into a pandemic and has extended all over the world. since the virus has the potential ability to severely impair heart and liver, analyzing the biochemical parameters is a suitable approach for clinicians to assess the outcome. methods: this study was conducted along with 614 recognized covid-19 patients. all samples were from emergency department of sina hospital in tehran, iran, from february to may, 2020. results: a total of 614 covid-19 patients with mean age of 57.8 years (16-94 years) consisting of 385 (62.7%) male and 229 (37.2%) female were studied. patients with covid-19 had no significant difference between cardiac and liver parameters on the presentation and discharge time (p-value≥0.05). patients with covid-19 had significant correlation in lactate dehydrogenase (ldh), aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), and total bilirubin with recovery and mortality outcome (p-value≤0.05). also, high sensitivity cardiac troponin-i, ldh, ast, and alt in patients with covid-19 were significantly associated with high in-hospital mortality (p-value<0.05). conclusion: several laboratory parameters may ease the evaluation of covid-19 in-hospital mortality. cardiac and liver parameters are critical in assisting covid-19 cases.