construction of a new silica-based nano-hybrid catalyst and its usage to manufacture bis(6-amino-1,3-dimethyluracil-5-yl) methanes

Initially, a novel inorganic-organic nano-hybrid catalyst titled si-propyl-functionalized n1,n1,n2,n2-tetramethylethane-1,2-diamine-n1,n2-diium chloride dihydrogen phosphate grafted with nano-silica (sptcds) was constructed, and its structure was verified by the following analyses: (i) x-ray diffraction (xrd), (ii) ft-ir, (iii) field emission scanning electron microscopy (fe-sem), (iv) thermogravimetry (tg), differential thermal gravimetric (dtg), and (v) energy-dispersive x-ray spectroscopy (edx). in the present study, effectual solvent-free fabrication of bis(6-amino-1,3-dimethyluracil-5-yl) methanes was accomplished using sptcds; in this protocol, 6-amino-1,3-dimethyluracil (2 eq.) that reacted with aryl aldehydes (1 eq.) to manufacture the uracil derivatives in satisfactory yields and reaction times.