synthesis of 3, 4-dihydropyrimidin-2-(1h)-ones using a hydrogel as a green and reusable catalyst

The primary objective of this study was to devise a straightforward and environmentally sustainable approach for creating biginelli compounds. accordingly, a p(amps) hydrogel served as an effective catalyst of diverse nature, facilitating the preparation of 3,4-dihydropyrimidine-2-(1h)-ones, commonly recognized as biginelli compounds. the chemical process unfolded using an eco-friendly method, resulting in notably abundant product yields. moreover, the catalyst exhibited remarkable reusability, maintaining its efficacy through four cycles without a substantial decline. the innovative biginelli reaction technique achieves environmentally conscious synthesis, robust product generation, simplified isolation procedures, catalyst sustainability, and avoids harmful by-products.