synthesis of new homogeneous amino acids compound with boron and some of its metal complexes

Synthesis of a synthetic ligand (l) by mixing histidine and boric acid in molar ratios of 2:1. the complexes of transition metal were prepared by reacting cocl2.6h2o, nicl2.6h2o, and cucl2.h2o with (l) in molar ratios of 2:1 (l:m). all produced compounds are investigated by using spectral methods uv-vis, ft-ir, 1h-nmr, and aas. in addition to the melting point, thermal analysis, magnetic susceptibility measurement, micro elemental analysis, and determination of chloride content. all complexes of transition metal were proposed to have octahedral geometries. every component was an electrolyte as well as a paramagnetic one. all the complexes of transition metal produced were shown to be antibacterial and antifungal against the bacteria staphylococcus aureus, klebsiella pneumonia, and the fungus candida. the anti-cancer activities of the ligand and copper complex were also studied.