electrochemical sensing of theophylline using modified glassy carbon electrode

In this work, three dimensional nio nanowrinkles (3d nio-nws) were prepared and used as electrode materials to modify the surface of a glassy carbon electrode (3d nio-nws/gce). then, differential pulse voltammetry (dpv), cyclic voltammetry (cv) and chronoamperometry (cha) were employed to determine the electrochemical response of theophylline on as-fabricated sensor. the electrochemical theophylline oxidation was elevated on the modified electrode. the peak current on the modified electrode in phosphate buffer solution (pbs, 0.1 m, ph=7.0) showed a linear elevation with an increase in the theophylline concentration (0.1-900.0 μm), with a narrow detection limit of 0.03±0.001 μm.