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synthesis and biological activities of some new derivatives based on 5-styryl-2-amino-1,3,4-thiadiazole
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نویسنده
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narran shetha fadhil ,mohammed suad salman ,omer maab khattab ,hussein iftikhar ahmed ,jawad noor mohammed ,shweish batool karim
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منبع
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chemical methodologies - 2022 - دوره : 6 - شماره : 2 - صفحه:83 -90
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چکیده
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In this research, 5-styryli-2-amino-1, 3, 4-thiadiazole [c1] was prepared from the reaction of acid 3-phenyl propenoic acid with thiosemicarbazide. amic acids [c2-c5] were synthesized by reactive compound [c1] with different types of hydrides, then [c2, c4] were treated with ac2o in the presence of naoac as a catalyst giving imide compounds [c6, c7]. the structure of the new derivatives was confirmed via ft-ir spectroscopy, some of which were confirmed via 1h-nmr spectroscopy. three of these new derivatives were evaluated by their esherichiacoli, staphylococcus, and rhizopus emporium.
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کلیدواژه
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4-thiadiazle ,amic acid ,imide ,anti-bacterial ,anti-fungal
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آدرس
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university of baghdad, college of science for women, department of chemistry, iraq, university of baghdad, college of science for women, department of chemistry, iraq, university of baghdad, college of science for women, department of chemistry, iraq, university of baghdad, college of science for women, department of chemistry, iraq, university of baghdad, college of science for women, department of chemistry, iraq, university of baghdad, college of science for women, department of chemistry, iraq
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پست الکترونیکی
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batool.karim@gmail.com
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Authors
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