investigation of ace inhibitory effect and antioxidant activity of peptide extracted from spirulina platensis

Spirulina platensis is a green-blue microalgae and a rich source of many nutrients such as protein, vitamins, and minerals. spirulina contains peptides that have therapeutic and beneficial effects on the human body. in this study, peptide ile-gln-pro from spirulina platensis was extracted using alcalase enzyme and purified by ultrafiltration and silica gel columns, and the fractions were identified using rp-hplc analysis. the molecular weight of the tripeptide was determined by gc/mass spectroscopy. the peptide extracted with a concentration of 6.23 mg/ml and a purity of 75.72%. then its inhibitory effect on angiotensin i-converting enzyme (ace) and its anti-oxidant properties were investigated using ddph (2,2-diphenyl-1-picrylhydrazyl) assay.