insight into the stability, reactivity, structural and spectral properties of the anti, syn-endo and syn-exo isomers of bis(n-ethoxy-n-ethyl-dithiocarbamato)nitrido technetium- 99m [99mtc-n(noet)2] radiopharmaceutical

(ethoxy(ethyl)amino)methanedithiol is used in nuclear medicines as a ligand for the preparation of diagnostic radiopharmaceuticals. among the available radionuclide tracers, technetium-99m (99mtc) is a good choice for myocardial perfusion imaging. among the various cardiac perfusion imaging agents, bis(n-ethoxy-n-ethyl- dithiocarbamato)nitride technetium-99m radiopharmaceutical has a very high uptake. during the present study, the reactivity, stability, structural and spectral properties of anti, syn-endo and syn-exo isomers of bis(n-ethoxy-n-ethyl-dithiocarbamato)nitride technetium-99m radiopharmaceutical were discussed by density functional theory (dft) computational method. it can be deduced from the theoretically applied computations that the anti- molecular structure is generally more stable than the syn-endo- and syn-exo- ones.