silica-imidazole solid catalyst for n-glycine derivatives synthesis

Schiff base was reacted with α-chloroacetic acid to produce n-(α-chlorobenzyl)-n-phenylglycine derivatives (n-gly) over solid heterogeneous catalyst. different n-gly derivatives were synthesized over the catalyst with approximately 90% yield. both calculated and theoretical elemental analyses of n-gly derivatives were in agreement with each other. the functional groups of n-gly derivatives were proved by the ft-ir spectroscopy. the melting points n-gly derivatives were matched with those in the literature. the catalyst was produced by immobilizing sodium silicate from rice husk with 3–(chloropropyl)triethoxysilane followed by refluxed the product with p-xylyl-di-imidazolium chloride. the results showed that the optimum catalyst conditions were 5 h as reaction time, 0.25 g mass of catalyst, 90 °c as reaction temperature, and toluene as the best solvent.