N,N,N',N'-Tetramethylethylene-Diaminium-N,N'-Disulfonic Acid Chloride As A Highly Effective Catalyst For the Synthesis of 4h-Pyrano[2, 3-C]Pyrazoles, Α-Carbamatoalkyl-Β-Naphthols and Α-Amidoalkyl-Β-Naphthols

In this work, n,n,n',n'-tetramethylethylene-diaminium-n,n'-disulfonic acid chloride {[tmedsa][cl]2} has been utilized as a highly effective catalyst in order to promote the following organic transformations under green, solvent-free and mild conditions: (i) the synthesis of 4h-pyrano[2, 3-c]pyrazoles from aromatic aldehydes, 3-methyl-1-phenyl-2-pyrazolin-5-one and malononitrile, (ii) the preparation of α-carbamatoalkyl-β-naphthols from arylaldehydes, β-naphthol and alkyl carbamates, and (iii) the production of α-amidoalkyl-β-naphthols from arylaldehydes, β-naphthol and amides.