One-Pot, Clean and Energy Efficient Synthesis of Dibenzo[B,F][1,4]Oxazepine Derivatives Promoted By Ultrasound

In the present study, a variety of dibenzo [b,f][1,4] oxazepine derivatives was successfully synthesized in good yields under ultrasonic irradiation as an environmental friendly technique. this one-pot method is practically reliable, mild, catalyst-free, and inexpensive. ultrasonic irradiation on the reaction mixture leads to fine emulsion between the reactants and violent collapses of a lot of cavitation bubbles in less than a microsecond releases extreme heat, leading to cross the activation energy barrier. in the absence of ultrasonic irradiation, a trace amount of the product was formed after 50 min. the superiority of the ultrasound irradiation over other methods in the synthesis of dibenzo [b,f][1,4] oxazepine derivatives is its low reaction temperature and operational simplicity in approximately same yields.