mathematical modeling of cancer‎: ‎sensitivity analysis of tumor growth rate and the effect of anti-tigit treatment dosage

This study develops a mathematical model for cancer using a system of nonlinear differential equations to analyze tumor dynamics and the effects of anti-tigit treatment‎. ‎by computing the net growth rate‎, ‎we evaluate the potential for tumor proliferation and establish its relationship with the stability of equilibrium points‎. ‎additionally‎, ‎a sensitivity analysis is conducted to identify the key parameters influencing tumor growth rate‎. ‎these insights are then utilized to inform the dosage of anti-tigit treatment‎, ‎to inform effective therapeutic strategies by targeting the most influential and‎‎adjustable factors.