Stem Cell Conditioned Medium as a Novel Treatment for Neuroinflamation Diseases

Inflammation is a most important factor that mentioned as causes of many neurodegeneration disease likeparkinson, alzheimer and als. neuroinflammation is poorly understood like neuroinflamation inalzheimer and parkinson. studies showed that even chronic peripheral inflammation that observe inmany diseases like arthritis can cause neurodegeneration and dementia in some cases. theneuroinflammation in many dementia diseases are local and information is limited about it. one of themost important treatments for dementia diseases like alzheimer is the use of anti-inflammatory drugs likensaids but unfortunately they have poor therapeutic effects on neuroinflammation. recent studiesinvestigated that conditioned medium extracted from mesenchymal stem cells have neuromodulatoreffects even could prevent neurodegeneration in some cases. in this study we review effects ofmesenchymal stem cell conditioned medium in different central nervous system (cns) disease associatedwith neuroinflammation.