hospital-acquired infections, bacterial causative agents and antibiotic resistance pattern in intensive care units at teaching hospitals in north of iran

Aim: hais (hospital-acquired infections) remain a major problem in icus. the purpose of this study is survey of hais and antibiotic susceptibility patterns of causative agent among patients admitted in icus. methods: a retrospective study was conducted in three teaching hospitals related to mazandaran university of medical sciences in 2012-2014. the incidence, clinical presentation, risk factors, causative agents and antibiotic resistance pattern of bacteria analyzed by spss (ver. 16) and descriptive statistics were used. results: the incidences of hais were 4.13%. the most common hais were respiratory infection 49.1%, wound infection 26.3%, uti 16.7%, and blood infection 7.9%. p. aeruginosa 42.1%, acinetobacter spp. 21.05%, enterobacteriaceae 19.29% and s. aureus 12.28% were the most bacteria isolated. we found that 35% esbl and 14.58% carbapenemase-producer pseudomonas spp. also 60% of acinetobacter spp were mdr and 14.28% of s.aureus was resistant to nivnmocnav. conclusion: this article suggests that the prevalence of hais in icus of teaching hospitals in northern iran is false low. diagnosing of ni in our area focused on physician diagnosis and clinical criteria for reporting hais, the rate of inappropriate administration of antibiotics is very high in our region also significant resistance in organisms such as acinetobacter spp, p. aeruginosa, enterobacteriaceae, s. aureus to the most commonly used antibiotics has been increasing. infection control procedures must be implemented carefully and antibiotic resistance patterns of organisms causing hais should be checked periodically to guide empirical antibiotic therapy.