the role of antibiotics therapy on maternal complication in women with premature rupture of membranes

Introduction: rupturing of fetal membranes before week 37 is called preterm premature rupture of membranes (pproms). the pathogenesis of pprom is not definite but it seems that many mechanical and physiological etiologies are involved. as the most important risk factors, having a late history of the same disease, genital infection, prepartum bleeding and smoking can be named. premature rupture of the membranes is usually seen in preterm births and it accounts for about 1/3 of them. methods: this interventional semi experiencing study was done on patients visiting the sayyad shirazi hospital in gorgan with a chief complaint of leaking fluid in week 24 up to 34 of pregnancy. noticeable neonatal complications in this study were birth time apgar, admission in nicu, birth weight and iugr. all of the neonates entered the study with a gestational age of fewer than 34 weeks and admitted with a diagnosis of probable sepsis. neonates with congenital abnormalities, asphyxia, respirational distress syndrome, meconium aspiration syndrome and birth weight less than 1000 gram exited the study. data was analyzed with spss16 statistical software and chi2 test, independent t-test and anova. findings: admission length time until labor in the group that did not receive antibiotics was less than the other group and average admission length time between the two groups was statistically meaningful (p=0.00). in the group that received antibiotics, on order 25, 50 and 75 percent of patients had admission length time of 7, 4 and 12 days and these percentages for the other group are 5, 3 and 7 days. also, there was not any significance difference between the other two variables, which are the type of labor and fever frequency, and chorioamnionitis. conclusion: according to the results, usage of antibiotics lengthens the late stage of labor and it is probably effective in decreasing the premature neonate complications. therefore using of antibiotics in premature rupture of amniotic fluid is suggested.