Bio Efficacy, and Photocatalytic Activity of the Silver Nanoparticles Synthesized From Cryptolepis Buchanani Leaf Extract

The objective of the study is to synthesis silver nanoparticles from the leaf extract of cryptolepis buchanani, a medically important plant,by green synthesis method. the synthesized nanoparticles have an average size of 17.05±5.27 nm, crystalline in nature with face cantered cubic structure, and positive surface charge. the nanoparticles are biologically active. it killed > 90 % of hela cells at 25 μg ml1 concentration invitro cell cytotoxicity assay, with a ld50 value of 3.98 μg ml1. the nanoparticles are less effective on mcf7 and hek293 cell line, almost 70 % of mcf7 populations were survived at highest concentration of 25 μg ml1. in case of hek293 it killed almost 78 % of cells at the same concentration with a 9.45 μg ml1 ld50 value. the synthesized nanoparticle lysed less than 2.5 % of red blood cells at 10 μg ml1 concentration invitro. the nanoparticles degraded >90 % of methylene blue dye in presence of light in 8.5 h. these properties of the synthesized nanoparticles are unique, and make it promising for its future potential applications.