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frequency of polymorphism alu insertion in progesterone receptor gene in endometriosis
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نویسنده
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ataei mohammad ,farashahi ehsan ,seifati morteza ,ghasemi nasrin
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منبع
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international journal of medical laboratory - 2016 - دوره : 3 - شماره : 3 - صفحه:185 -190
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چکیده
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Background and aims: this research aimed to study a possible link between endometriosis and polymorphism of the progesterone receptor gene. materials and methods: the control group consisted of 86 women without endometriosis and the case group comprised 86 patients with a diagnosis of endometriosis by laparoscopy. genotypes for alu insertion polymorphisms (a1/a1, a1/a2 and a2/a2) were described by polymerase chain reaction and determined on a 2% agarousegel. results: the genotype frequencies of a1/a2 and a2/a2 were not significantly higher in patients than in the control group without endometriosis. on the other hand differences in the alu insertion polymorphism frequencies were not significant. conclusion: according to our investigations, we conclude that there is not a significant correlation between alu insertion polymorphism and endometriosis.
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کلیدواژه
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endometriosis ,polymerase chain reaction ,progesterone receptor gene
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آدرس
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shahid sadoughi university of medical science, international campus, department of medical genetics, ایران, shahid sadoughi university of medical science, faculty of medicine, department of medical genetics, ایران, islamic azad university, ashkezar branch, department of genetics, ایران, shahid sadoughi university of medicinal sciences, recurrent abortion research centre, reproductive sciences institute, ایران
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پست الکترونیکی
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nghasemi479@gmail.com
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Authors
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