the effect of four-week vibration training on adiponectin and fibrinolysis markers levels in overweight women

Sedentary lifestyle is one of the factors causing pathophysiological problems such as the impairments in coagulation and fibrinolysis systems. the present study aimed to examine the effect of 4-week whole-body vibration training on tissue plasminogen activator (tpa), plasminogen activator inhibitor type 1 (pai-1), and adiponectin in overweight women. the research was an applied quasi-experimental study with an experimental group and a control group using pretest-posttest design. in this interventional study, 45 employed women with the age range of 25-40 years and body mass index of 25-29.5 kg/m2 were introduced by the national olympic academy. the participants who met the inclusion criteria were then randomly assigned to two experimental and control groups. the vibration training was performed for 4 weeks. paired and independent t-test was used to statically analyses. the tpa level significantly increased in the vibration training group (p = 0.01), and there was a significant difference between the tpa levels of the two groups in the post-test phase (p = 0.01). furthermore, pai-1 value ​​also decreased significantly in the vibration training group (p = 0.004), and the tpa / pai-1 ratio also dropped significantly after 4 weeks of vibration training (p = 0.03). with 4 weeks of vibration training, adiponectin increased meaningfully (p = 0.02), and there was a significant difference between the two groups in this regard in the post-test phase (p = 0.01). vibration training decreases tpa / pai-1 so that the vibration training plays a critical role in increasing adiponectin, enhancing blood flow of the muscles and adipose tissues, and decreasing fat percentage.