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Health-related quality of life in premature acute coronary syndrome: Does patient sex or gender really matter?
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نویسنده
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leung yinko s.s.l. ,pelletier r. ,behlouli h. ,norris c.m. ,humphries k.h. ,pilote l. ,karp i. ,bacon s.l. ,cox j.l. ,dasgupta k. ,daskalopoulou s.s. ,eisenberg m.j. ,engert j.c. ,ghali w.a. ,khan n.a. ,lavoie k.l. ,rabi d. ,so d. ,stark k.d. ,tagalakis v. ,tsadok m.a. ,thanassoulis g. ,shimony a.
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منبع
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journal of the american heart association - 2014 - دوره : 3 - شماره : 4
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چکیده
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Background-limited data exist as to the relative contribution of sex and gender on health-related quality of life (hrql) among patients with acute coronary syndrome (acs). this study aims to evaluate the effect of sex and gender-related variables on longterm hrql among young adults with acs. methods and results-genesis-praxy (gender and sex determinants of cardiovascular disease: from bench to beyond- premature acute coronary syndrome) is a multicenter,prospective cohort study (january 2009 to august 2013) of adults aged 18 to 55 years,hospitalized with acs. hrql was measured at baseline,1,6,and 12 months using the short form-12 and seattle angina questionnaire (saq) among 1213 patients. median age was 49 years. women reported worse hrql than men over time post-acs,both in terms of physical and mental functioning. gender-related factors were more likely to be predictors of hrql than sex. femininity score,social support,and housework responsibility were the most common gender-related predictors of hrql at 12 months. we observed an interaction between female sex and social support (β=0.44 [95% confidence interval,0.01,0.88]; p=0.047) for the physical limitation subscale of the saq. conclusions-young women with acs report significantly poorer hrql than young men. gender appears to be more important than sex in predicting long-term hrql post-acs. specific gender-related factors,such as social support,may be amenable to interventions and could improve the hrql of patients with premature acs. © 2014 the authors.
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کلیدواژه
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Angina; Cardiovascular diseases; Myocardial infarction; Sex
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آدرس
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division of clinical epidemiology,mcgill university health centre,montreal,qc, Canada, division of clinical epidemiology,mcgill university health centre,montreal,qc, Canada, division of clinical epidemiology,mcgill university health centre,montreal,qc, Canada, faculties of nursing,medicine and school of public health,university of alberta,edmonton,ab, Canada, division of cardiology,department of medicine,university of british columbia,vancouver,bc,canada,providence health care research institute,st. paul's hospital,vancouver,bc, Canada, division of clinical epidemiology,mcgill university health centre,montreal,qc,canada,division of general internal medicine,mcgill university health centre,montreal,qc, Canada, university of montréal hospital research center (crchum),department of social and preventive medicine,university of montréal,montréal,qc, Canada, concordia university and research center,hôpital du sacré-coeur de montréal,montréal,qc, Canada, department of medicine and of community health and epidemiology,dalhousie university,halifax,ns, Canada, research institute of the mcgill university health center,montréal,qc, Canada, research institute of the mcgill university health center,montréal,qc, Canada, jewish general hospital,mcgill university,montréal,qc, Canada, research institute of the mcgill university health center,montréal,qc, Canada, university of calgary,calgary,ab, Canada, university of british columbia,vancouver,bc, Canada, university of quebec at montréal (uqam) and research center,hôpital du sacré-coeur de montréal,montréal,qc, Canada, university of calgary,calgary,ab, Canada, university of ottawa heart institute,ottawa,on, Canada, department of kinesiology,university of waterloo,waterloo,on, Canada, mcgill university,divisions of internal medicine and center for clinical epidemiology and community studies,jewish general hospital,montréal,qc, Canada, research institute of the mcgill university health center,montréal,qc, Canada, research institute of the mcgill university health center,montréal,qc, Canada, jewish general hospital,mcgill university,montréal,qc, Canada
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Authors
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