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   A Glance At Berberis Integerimma Pharmacological Effects and Its Active Constituents  
   
نویسنده Moein Mahmoodreza ,Sabahi Zahra ,Salim Hasti
منبع Trends In Pharmaceutical Sciences - 2020 - دوره : 6 - شماره : 1 - صفحه:1 -10
چکیده    Berberis integerrima (family: berberidaceae) is broadly used in the pharmacological studies as a rich source of active compounds. among different compounds, alkaloids are the most isolated ones from various parts of this plant. research in available databases including web of science, pub med and google scholar was used to reveal the pharmacological effects and active compounds of b. integerrima. the present review attempts to give a short overview on biological effects and active components of b. integerrima with emphasis on some mechanisms of activities. scientific evidences suggest possible therapeutic properties of this plant on diseases such as diabetes, inflammation, free radicals associated diseases, seizure and cancer. in this review, we evaluated the most correlated original articles to determine the effects of b. integerrima on different medical conditions. it seems that b. integerrima would be useful in managing various types of disease, however more studies, particularly pharmacokinetic and clinical trials, need to be considered to improve our knowledge about toxicity and possible side effects of this plant.
کلیدواژه Berberis Integerrima ,Alkaloid ,Berberine ,Phytochemical Constituents
آدرس Shiraz University Of Medical Sciences, Medicinal Plants Processing Research Center, School Of Pharmacy, Department Of Pharmacognosy, Iran, Shiraz University Of Medical Sciences, Medicinal Plants Processing Research Center, Iran, Shiraz University Of Medical Sciences, Medicinal Plants Processing Research Center, Iran
 
     
   
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