Physiological and Pharmacological Properties of the Swertia longifolia Boiss Plant and Its Compounds: A Mini Review

Swertia longifolia, from the gentianaceae family, grows in various regions of the world and is used in traditional and modern medicine to treat many diseases. the present study aimed to systematically review the physiological-pharmacological effects of this plant and its compounds. to conduct this scoping review, articles published in pubmed, sciencedirect, web of science, google scholar, proqest, cochrane, sid, and magiran databases were searched, using the keyword s. longifolia, on 18th march, 2023 to find relevant articles. s. longifolia contains effective compounds such as xanthones, iridoid glycosides, flavonoids, and triterpenoids, which have antioxidant, anti-cholinesterase, and anti-cytotoxic properties. moreover, the extract of this plant and its compounds have anti-diabetic, hepatoprotective, and hypolipidemic properties and can inhibit the enzyme acetylcholinesterase. given the effects of the extract and compounds of s. longifolia in the treatment of various diseases, it seems that clinical trials as well as more advanced studies should be conducted on each of the compounds of the plant which will be considered as new candidates for drug development in the future.