triply periodic minimal surfaces scaffolds and their comparison with cancellous bone: fluid flow point of view‎

The present study investigated bone growth characteristics, such as permeability, wall shear stress, and surface-to-volume ratio. then by comparing them with the properties of cancellous bone, the most desirable scaffolds for bone cell growth have been selected. nine porous triply periodic minimal surfaces scaffolds in the exact unit cell sizes in four porosities have been designed. because of the implantation of scaffolds in the body, non-newtonian fluids can lead to more realistic results. hence, the non-newtonian model of the blood has also been examined for comparison with the newtonian model. the results have shown that the permeability for newtonian fluids was dependent only on the geometry of the scaffold, and it was intrinsic. still, in non-newtonian blood fluid, the permeability has been several times smaller than in the newtonian model. also, the average wall shear stress in the non-newtonian model of blood has been almost twice as large as in the newtonian model. finally, by considering the permeability of cancellous bones ( ), scaffolds which effectively mimicked the characteristics of this type of bone have been identified. the fischer-koch s scaffold has the highest permeability among these four scaffolds, and schwartz diamond 2 scaffold has the closest permeability to cancellous bone. this proved that selecting the most desirable scaffold is complex and challenging and should be chosen according to its conditions and application.