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the association between dietary polyphenols intake and risk of liver cancer: a systematic review and meta-analysis of observational studies
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نویسنده
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emrani arezoo sadat ,mirjalili fatemeh ,yekrang safakar hooman ,forootani bita ,salehi-abargouei amin
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منبع
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journal of nutrition and food security - 2025 - دوره : 10 - شماره : 2 - صفحه:328 -337
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چکیده
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Background: the current data on the association between dietary polyphenols intake and liver cancer are not conclusive. therefore, we aimed to perform a systematic review and meta-analysis of observational studies on the association between dietary polyphenol intake and liver cancer. methods: a systematic search of online databases, including pubmed/medline, scopus, and web of science, was conducted until august 2024. observational studies that investigated the association between dietary intake of polyphenols and the risk of liver cancer were included. the overall effects were assessed using the random effects model. results: totally, four studies were eligible to be included in the systematic review, and for meta-analysis, 3 studies with 4 effect sizes were included. the overall association between dietary intake of isoflavones and the risk of liver cancer was not significant (p=0.35, 95% ci: 0.58-1.21). conclusion: no significant association was found between dietary polyphenols intake and liver cancer risk. further observational studies are suggested to confirm these findings.
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کلیدواژه
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polyphenols; isoflavones; liver neoplasms; hepatocellular cancer
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آدرس
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shahid sadoughi university of medical sciences, school of public health, research center for food hygiene and safety, department of nutrition, iran, shahid sadoughi university of medical sciences, school of public health, research center for food hygiene and safety, student research committee, department of nutrition, iran, shahid sadoughi university of medical sciences, school of public health, research center for food hygiene and safety, department of nutrition, iran, shahid sadoughi university of medical sciences, school of public health, research center for food hygiene and safety, department of nutrition, iran, shahid sadoughi university of medical sciences, school of public health, research center for food hygiene and safety, yazd cardiovascular research center, non-communicable diseases research institute, department of nutrition, iran
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پست الکترونیکی
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abargouei@gmail.com; abargouei@ssu.ac.ir
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Authors
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