the effect of resistance training on levels of interlukine-6 and high-sensitivity c - reactive protein in older-aged women

Introduction: aging is associated with elevated levels of some proinflammatory factors and exercise is a non-invasive intervention to improve immune function among older adults .the aim of the study was to compare resistance training effects on interlukine-6 (il-6) and high-sensitivity c-reactive protein (hs-crp) levels in older-aged women. methods: the study was quasi-experimental and forty healthy females were selected and randomly assigned to one of four groups: strength after endurance training (endurance + strength (e + s), n = 9), strength prior to endurance training (strength + endurance (s + e), n = 10), interval resistance-endurance training (int, n = 12), and control (n = 9) groups. the training program was performed for eight weeks, three times per week. human tnf-α and il-6 sandwich elisa kit were used. within-group differences were analyzed using a paired samples t-test and between-group differences were analyzed using one-way analysis of variance. results: the intra-session order had not significantly influence on the adaptive response of waist-to-hip ratio (p = 0.55), il-6 (p = 0.55) and hs-crp (p = 0.55) throughout the study. however, significant differences were shown following combined training between the s + e, e + s and int groups for vo2 max (p = 0.029), body mass (p = 0.016) and bmi (p = 0.023) when comparing pre and posttests. conclusion: this study confirmed that adaptations to a combination of endurance and resistance training appear to be independent of whether resistance training occurs prior to or following endurance training.