electrochemical study of some charge-transfer complexes involving amitriptyline and nortriptyline and determination of drugs
|
|
|
|
|
نویسنده
|
bagheri gh. a.
|
منبع
|
iranian journal of analytical chemistry - 2015 - دوره : 2 - شماره : 1 - صفحه:50 -56
|
چکیده
|
Spectrophotometric and electrochemical studies were successfully used in quantitative analysis of amitriptyline hydrochloride (ath) and nortriptyline hydrochloride (nth). conductometric titration were carried out in equeous solution using iodide and dopamine and serotonine as titrant. two new methods using spectrophotometry are dascribed for the determination of (ath) and (nth) with potassium bromate as the oxidizing agent and acid dyes, methyl orange and indigo carmine. both spectrophotometric methods are based on the oxidation of mentioned drugs by a known excess of bromate in acid medium and in the presence of excess of bromide followed by estimation of surplus oxidant by reacting with either indigo carmine (method a) or methyl orange (method b) and measuring the absorbance at 609 or 507 nm.
|
کلیدواژه
|
conductometry ,amitriptyline hydrochloride ,nortriptyline hydrochloride ,dopamine hydrochloride ,serotonine hydrochloride ,iodine
|
آدرس
|
islamic azad university, center tehran branch, department of chemistry, ایران
|
پست الکترونیکی
|
azar.bagheri@iauctb.ac.ir
|
|
|
|
|