effects of six-week endurance training in liver enzymes, lipid profile, interleukin-6 and high-sensitivity c-reactive protein (hs-crp) responses in people with a family history of coronary artery disease

Background: research on the effects of moderate-intensity endurance training on inflammatory indices and cardiovascular risk factors is limited. objectives: the aim of this study was to determine the effects of six weeks of endurance training on liver enzymes, body composition, lipid profile, interleukin-6, and c-reactive protein responses in people with a family history of coronary artery disease (cad). methods: thirty men (30 - 45years) participated in this study who were divided into two groups, including the control group (n = 10) and training group (n = 20) systematically. the training group program consisted of running on a treadmill for 30 minutes with an intensity of 55 to 60% of maximum heart rate. these training programs were continued three times a week for six weeks. the control group did not perform any exercise program. elisa technique was used to measure lipid profile, liver enzymes, interlukin-6 (il-6), and high-sensitivity c-reactive protein (hs-crp), respectively. results: the results showed that the variables of weight, liver enzymes, lipid profile, il-6, and hs-crp were significantly different from the pre-test (p < 0.05). also, in between-group comparison, the results showed that except for the variables of fat percentage and bmi in the other variables of the study, a significant difference was observed (p < 0.05). conclusions: the results of this study suggest that moderate-intensity endurance training could be used as a useful way to reduce weight, levels of inflammatory markers, liver enzymes and cardiovascular risk factors in people with a family history of cad.