Study the activity of Tryptase and Beta 2- Microglobulin Levels in the Sera of Patients With Chronic Renal Failure and Rheumatoid Arthritis

This work was mainly designed to study the levels of mast cell tryptase & beta 2- microglobulin in serum of patients with chronic renal failure (crf), which they were in the end stage of renal disease (esdr) depending on hemodialysis (hd) and chronic renal failure patients with rh.arthritis called ( renal osteodystrophy). blood samples were collected from kirkuk general hospital, with their ages between (20-70) years. this study included (135) blood samples including (85) sample for patients with chronic kidney failure and (25) samples for patients with kidney failure and rh.arthritis in addition to (25) samples from subjects apparently healthy as control group. results were obtain a highly significant increase (p<0. 001) in the levels of tryptase and beta2 -microglobulin in serum of patients with chronic renal failure and renal osteodystrophy disease comparwith normal individuals